The most important thing about organic grape seed extract powder is that it contains procyanidins. Proanthocyanidins (OPC for short) is a natural plant polyphenolic substance present in grapes. Grape seed extract OPC has very strong in vivo activity. According to reports, the anti-oxidation and free radical scavenging ability of proanthocyanidins is 20 times that of vitamin C and 50 times that of vitamin E. It is internationally recognized as the most powerful natural antioxidant for scavenging free radicals in the human body.
After decades of research, at the end of the 20th century, scientists confirmed that it has many functions such as inhibiting and scavenging free radicals, anti-oxidation, anti-radiation, anti-tumor, anti-allergic, anti-aging and improving heart and cerebrovascular activity. a biological effect.
In short, there are many benefits~ It is widely used in the fields of medicine, health care products, food, cosmetics and clinical treatment of diseases.
1. Beauty and beauty: moisturizing skin, anti-ultraviolet, anti-radiation
Europeans call proanthocyanidins youth nutrition, skin vitamins, and oral cosmetics. Because it restores the vitality of collagen, making the skin smooth and elastic. Collagen is the building block of skin and is the gel-like substance that holds our body together. Vitamin C is an essential nutrient for biochemical synthesis of collagen
Proanthocyanidins make more vitamin C effective, which means that vitamin C can more easily perform all its functions (including collagen production).
Proanthocyanidins are attached to collagen, which can prevent the damage of enzymes that destroy collagen. Proanthocyanidins not only help collagen fibers form a cross-linked structure, but also help restore damage caused by excessive cross-linking caused by injuries and free radicals. Excessive cross-linking suffocates and hardens connective tissue, which wrinkles and prematurely ages the skin.
Because anthocyanins can effectively prevent and reduce the damage to the skin caused by ultraviolet radiation, inhibit lipid peroxidation caused by free radicals; reduce the damage caused by radiation from computers, mobile phones, and TVs to the skin and internal organs. Grape seed extract is a natural sunscreen, which can block ultraviolet rays from damaging the skin, and can also repair damaged collagen and elastic fibers.
Grape seed extract also has a miraculous function, that is, it has astringent effect, which can tighten the skin and prevent the early appearance of skin wrinkles. Long-term use can make the skin smooth and elastic, and has the effect of beautifying and beautifying the skin.
2. Protect the cardiovascular and cerebrovascular system
Since free radicals and oxidative stress are important causes of many cardiovascular diseases, and intake of OPC can provide the body with powerful antioxidant support, organic grape seed extract powder has a wide range of cardiovascular protection effects.
The most notable effects are:
①Anti-myocardial oxidative damage
Studies have shown that OPC can reduce the formation of oxidants in primary cultured chicken embryonic ventricular myocytes, and significantly improve the survival rate and contractile function of cells. OPC can also improve doxorubicin-induced myocardial oxidative damage. As an anticancer drug, doxorubicin can significantly inhibit the growth of sarcoma 180 by intraperitoneal injection of tumor-bearing mice, but it can also cause the reduction of superoxide dismutase and glutathione peroxidase activities in the myocardium, the heart and serum Adverse reactions of myocardial oxidative damage such as elevated malondialdehyde in The intragastric administration of OPC not only significantly enhanced the anticancer effect of doxorubicin, but also completely inhibited the myocardial oxidative damage induced by doxorubicin.
② Anti-atherosclerosis
Atherosclerosis (AS) is one of the most serious and common cardiovascular diseases affecting human health. The morbidity and mortality are on the rise, and the age of onset is getting earlier and earlier. At present, hyperlipidemia is considered to be an important cause of AS lesions. Experiments have shown that grape seed extract has a hypolipidemic effect on experimental hyperlipidemia in rats. Its blood lipid-lowering effect is to reduce serum and liver tissue total cholesterol (TC) and increase serum high-density lipoprotein (HDL-C). C-reactive protein is a protein that appears in serum in certain diseases, and it is positively correlated with the degree of AS lesions. Although OPC can't bring it back to normal, it can prevent it from rising further. Thus, OPC can significantly improve the incidence of AS.
③ Anti-myocardial ischemia-reperfusion injury
Myocardial ischemia-reperfusion injury is mainly related to oxygen free radical damage.
Studies have shown that: OPC can significantly improve the left ventricular function after cardiac ischemia-reperfusion, reduce the size of myocardial infarction, and reduce the incidence of ventricular fibrillation. Its mechanism may be related to OPC directly scavenging peroxyl radicals and hydroxyl groups, reducing the damage of lipid peroxidation and its harmful metabolites to myocardial cell membranes, reducing oxidative stress during ischemia-reperfusion, and maintaining normal cell membranes. Permeability, reducing the release of myocardial enzymes and so on.
④ blood pressure lowering
With age, the elastic fibers in the arteries gradually oxidize and harden. This change is the main cause of hypertension in the elderly. Proanthocyanidins from grape seed extract can lower blood pressure by improving blood vessel elasticity. Animal experiments and clinical studies also show that grape seeds can lower blood pressure by lowering cholesterol levels, reducing cholesterol deposition on blood vessel walls and inhibiting the activity of angiotensinase.
⑤Protect the nerves (elements)
The damage to neurons caused by cerebral ischemia-reperfusion is mainly due to the interruption of blood supply to the brain, hypoxia, decreased glucose supply, and the occurrence of peroxidative reactions. Experiments have found that OPC has a protective effect on neuronal damage in cerebral ischemia, and its mechanism may be to scavenge free radicals and inhibit DNA damage.
⑥ Delay Alzheimer's disease
A study in the United States shows that the grape seed polyphenol extract obtained from grape seeds can reduce Alzheimer's disease, the formation of beta amyloid plaques in the brains of experimental mice, and help delay the memory of diseased mice diminished. OPC has many different cardiovascular protection mechanisms, and it will be a potential botanical drug for improving cardiovascular and cerebrovascular health.
3. Enhance immune function
①Promote wound healing
During the wound healing process, since the new tissue needs a large amount of energy supply, and the blood vessels in the wound area are damaged, the wound area is prone to tissue hypoxia. Meanwhile, angiogenesis also plays an important role in wound repair. OPC can significantly enhance the expression and release of vascular epidermal growth factor (VEGF). It can promote wound healing, and its effect is related to the regulation of the oxidation-reduction microenvironment of the wound area.
② Facilitate tissue repair
Comparing OPC as a tissue fixative with the commonly used tissue fixative glutaraldehyde (GA), it is found that OPC is much less toxic than GA in terms of cytotoxicity, and OPC-fixed tissues can resist the degradation of bacterial collagenase in vitro. No degradation was found within 6 weeks in vivo, and the migration and proliferation of fibroblasts were more pronounced in OPC-fixed tissues compared with GA, and the expression and deposition of collagen were also more significant. This characteristic of OPC will be of great significance for the repair or replacement of tissue damage or loss.
③Relieve allergic symptoms
Organic grape seed extract powder can inhibit the activity of histamine, the substance that triggers allergies, maintain smooth blood circulation in sensitive parts of the body, avoid continued inflammation and expansion of blood vessels, and protect normal cells to prevent the spread of allergies.
